Preoperative Point of Care Ultrasound Guided Fluid Optimization and Intravenous Ondansetron to Prevent General Anesthesia-Induced Hypotension

NANot yet recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

May 1, 2028

Study Completion Date

May 1, 2028

Conditions
Intra-operative Hypotension
Interventions
DRUG

fluid boluses guided by IVC diameter via US/administration of pre-operative IV Odansetrone

"group A will undergo fluid repletion guided by their IVC-CI - if a collapsible IVC, defined as a CI equal or greater than 43%, is observed, patients will receive repeated Lactated Ringer's 500 ml boluses followed by repeated IVC-CI measurements until their CI is less than 43%, and up to 1.5L.~Group B will undergo the same intervention, with the addition of intravenous ondansetron 4 mg in 10 ml normal saline 20 minutes before induction of general anesthesia."

Trial Locations (1)

Unknown

Meir Medical Center, Kfar Saba

Sponsors
All Listed Sponsors
lead

Meir Medical Center

OTHER