Demyelination and Remyelination in Multiple Sclerosis (MS) Detected by Brain Amyloid PET-CT

NACompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

July 27, 2021

Primary Completion Date

November 15, 2023

Study Completion Date

January 9, 2024

Conditions
Multiple Sclerosis
Interventions
DIAGNOSTIC_TEST

18F-florbetaben PET/CT

"The PET/CT study will be performed using a dual time acquisition protocol consisting of an early acquisition and a late acquisition.~Early acquisition Early acquisition starts with the patient already positioned on the PET/CT bed and venous access available.~A low-dose CT scan is performed for attenuation correction, the PET acquisition is started in list mode and a couple of seconds after the start, 300 MBq of 18F-Florbetaben is administered followed by washing with 10 ml of saline.~Early acquisition will last 30 minutes. Late acquisition A low-dose CT scan is performed to correct for attenuation and anatomical localisation, followed by a 20-minute list mode PET acquisition so that images are acquired after 90 minutes (tolerance: +10 minutes) of radiopharmaceutical uptake."

Trial Locations (1)

27100

ICS Maugeri SpA SB IRCCS, Pavia

All Listed Sponsors
lead

Istituti Clinici Scientifici Maugeri SpA

OTHER

NCT05783934 - Demyelination and Remyelination in Multiple Sclerosis (MS) Detected by Brain Amyloid PET-CT | Biotech Hunter | Biotech Hunter