Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08）

PHASE2RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

March 23, 2023

Primary Completion Date

December 30, 2025

Study Completion Date

December 30, 2025

Conditions

Advanced Biliary Tract Cancer

Interventions

DRUG

Sintilimab

a PD-1 immune checkpoint inhibitor

DRUG

Lenvatinib

Lenvatinib capsules

PROCEDURE

Cryoablation

Cryoablation is performed under US or CT guidance per Investigator decision

Trial Locations (1)

RECRUITING

Fudan University Shanghai Cancer Center, Shanghai

All Listed Sponsors

lead

Fudan University

OTHER