Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

PHASE3RecruitingINTERVENTIONAL

Enrollment

126

Participants

Timeline

Start Date

April 5, 2023

Primary Completion Date

November 1, 2026

Study Completion Date

November 1, 2028

Conditions

Breast Cancer

Interventions

RADIATION

Group 1 (preoperative radiation hypofractionated)

radiation schedules/regimens before your scheduled breast surgery

OTHER

Group 2 (preoperative radiation conventionally fractionated)

radiation schedules/regimens before your scheduled breast surgery

Trial Locations (1)

RECRUITING

M D Anderson Cancer Center, Houston