Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

June 1, 2028

Study Completion Date

September 1, 2028

Conditions
Heart FailureLeft Bundle-Branch BlockIschemic CardiomyopathyNon-ischemic Dilated CardiomyopathyLeft Ventricular DysfunctionLeft Ventricular DyssynchronyLeft Ventricle Remodeling
Interventions
DEVICE

Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Biventricular Pacing

The local anesthesia will be performed on the left/right subclavian area after prepping the skin. A horizontal incision will be performed. The cephalic and subclavian veins will be used to leads deliver. The active-fixation defibrillation lead will be placed to the apex/interventricular septum. The atrial active-fixation lead will be implanted to the right atrial appendage/interatrial septum. The implantation of the left ventricular pacing lead will be performed by cannulating one of the tributaries of the coronary sinus using delivery system. Leads will be fixated, connected with CRT-D device and placed in subcutaneous (subfascial prepectoral)/submuscular pocket. The pocket will be closed by separate stitches (2-4 suffice) using the resorbable braided suture. Cardioverter-defibrillator with a resynchronization function will be programmed for biventricular pacing.

DEVICE

Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Left Bundle Branch Pacing

The local anesthesia will be performed on the left/right subclavian area after prepping the skin. A horizontal incision will be performed. The cephalic and subclavian veins will be used to leads deliver. The active-fixation defibrillation lead will be placed to the apex/interventricular septum. The atrial active-fixation lead will be implanted to the right atrial appendage/interatrial septum. The implantation to the left bundle branch will be performed by using special delivery system. Leads will be fixated, connected with CRT-D device and placed in subcutaneous (subfascial prepectoral)/submuscular pocket. The pocket will be closed by separate stitches (2-4 suffice) using the resorbable braided suture. Cardioverter-defibrillator with a resynchronization function will be programmed left bundle branch pacing.

Trial Locations (1)

Unknown

RECRUITING

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk

All Listed Sponsors
lead

Tomsk National Research Medical Center of the Russian Academy of Sciences

OTHER