Depth of Botulinum Neurotoxin Injection for Treatment of Glabellar Lines

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 14, 2023

Primary Completion Date

June 20, 2023

Study Completion Date

December 31, 2025

Conditions
Glabellar Frown Lines
Interventions
DRUG

onabotulinumtoxinA at a depth of 2mm

One time administration of onabotulinumtoxinA to the corrugator supercilii muscles bilaterally. Dosing dependent on the baseline mass and volume of subject's glabellar muscles as assessed by trained cosmetic dermatologist, accounting for symmetry/asymmetry of the face and can range from 10-50 units. Will be administered at a depth of 2mm

DRUG

onabotulinumtoxinA at a depth of 4mm

One time administration of onabotulinumtoxinA to the corrugator supercilii muscles bilaterally. Dosing dependent on the baseline mass and volume of subject's glabellar muscles as assessed by trained cosmetic dermatologist, accounting for symmetry/asymmetry of the face and can range from 10-50 units. Will be administered at a depth of 4mm

Trial Locations (1)

48202

Henry Ford Health System, Detroit

All Listed Sponsors
lead

Henry Ford Health System

OTHER