The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial

NANot yet recruitingINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

February 1, 2026

Primary Completion Date

February 1, 2027

Study Completion Date

June 28, 2027

Conditions
Root CariesNaFSDFTooth Mousse
Interventions
OTHER

Group A

Application of SDF (silver diamine fluoride) solution on the root caries lesions twice yearly in a professional setting. Application of Placebo tooth mousse by the subject twice daily. Regular tooth brushing with standardized fluoridated toothpaste.

OTHER

Group B

Application of Sodium Fluoride varnish on the root caries lesions twice yearly in a professional setting. Application of Placebo tooth mousse by the subject twice daily. Regular tooth brushing with standardized fluoridated toothpaste.

OTHER

Group C

Application of Placebo varnish (water-based) solution on the root caries lesions twice yearly in a professional setting. Application of Biosmalto tooth mousse by the subject twice daily. Regular tooth brushing with standardized fluoridated toothpaste.

OTHER

Group D

Application of Placebo varnish (water-based) solution on the root caries lesions twice yearly in a professional setting. Application of Placebo tooth mousse by the subject twice daily. Regular tooth brushing with standardized fluoridated toothpaste.

Trial Locations (1)

3007

Zahnmedizinklinik University of Bern, Department of Restorative, Preventive and Paediatric Dentistry, Bern

All Listed Sponsors
lead

University of Bern

OTHER