900
Participants
Start Date
June 8, 2023
Primary Completion Date
September 30, 2027
Study Completion Date
September 30, 2027
Bisphosphonate
Medicine used to treat bone problems, called osteopenia or osteoporosis.
Resistance Training/Bone-Loading Exercise
Exercise in small groups three days per week under the supervision of exercise physiologists. Heart rate and blood pressure will be measured before and after each session and participants will warm-up by walking or cycling for five minutes at a slow pace. All RT exercises will be conducted on machines which accommodate different body sizes and allow small increments in resistance, both important considerations for low functioning older adults with obesity.
Placebo
Capsules identical to the active alendronate capsules without any active ingredients with the same dosing and follow up as BIS treatment group.
RECRUITING
Atrium Health Wake Forest Baptist, Winston-Salem
RECRUITING
University of Colorado Anschutz Medical Campus, Aurora
National Institute on Aging (NIA)
NIH
Wake Forest University Health Sciences
OTHER