Cardiovascular Effects of Norepinephrine

RecruitingOBSERVATIONAL
Enrollment

49

Participants

Timeline

Start Date

April 21, 2023

Primary Completion Date

March 21, 2025

Study Completion Date

December 21, 2025

Conditions
Septic Shock
Interventions
OTHER

transthoracic echocardiography

"* Concerning the main judgment criterion and the secondary judgment criteria:~ * Left ventricular ejection fraction (LVEF) by the Simpson Biplane method,~ * Cardiac output and cardiac index by continuity equation (measurement of left ventricular outflow chamber (mm) and sub-aortic time-velocity integral (cm/s)).~ * Tricuspid Annular Systolic Excursion (TAPSE) (mm)~ * S wave at the tricuspid ring (cm/s)~* Other parameters collected systematically:~ * Surface of the left ventricle (end-systolic and end-diastolic),~ * Global strain of the left ventricle~ * Mitral Annular Plane Systolic Excursion (MAPSE) (mm)~ * Left ventricular filling pressure (LVRP) (at the mitral annulus, E, A, e', S' waves, E/A ratio, E/e');~ * Maximum tricuspid regurgitation velocity (m/s) to estimate systolic pulmonary arterial pressure (PAPs) (mmHg)"

Trial Locations (1)

51092

RECRUITING

Chu Reims, Reims

All Listed Sponsors
lead

CHU de Reims

OTHER