Intermittent Fasting Versus Carbohydrate Drinks Before Surgery

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

March 20, 2023

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Perioperative CareIntermittent FastingCarbohydrate LoadingPreoperative FastingOrthopedic SurgeryInsulin Resistance
Interventions
BEHAVIORAL

Time-restricted feeding

Subjects in the will be instructed to follow a TRF regimen consisting of a daily 8h ad libitum eating period and 16h water fasting period during the last 2 weeks before surgery. Participants will be encouraged to begin their eating period at 08:00h and end it at 16:00h, since the metabolic benefits of TRF appear to be considerably more pronounced when the eating period starts early in the day.

DIETARY_SUPPLEMENT

Carbohydrate loading

Subjects will continue their usual diet and will receive two quantities of a clear beverage containing 12.5 g/100 mL maltodextrin (50 kCal/100 mL, pH 5.0); 800 mL at 22.00h on the evening before surgery and 400 mL two hours before anaesthesia induction.

Trial Locations (1)

1105AZ

RECRUITING

Amsterdam UMC location AMC, Amsterdam

All Listed Sponsors
collaborator

European Society of Anaesthesiology and Intensive Care

OTHER

lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER