20
Participants
Start Date
December 8, 2020
Primary Completion Date
June 12, 2023
Study Completion Date
June 12, 2023
Non-buffered Anesthetic
non-buffered LA, 2% lidocaine with epinephrine 1:100,000
Buffered Anesthetic
A cartridge of 2% lidocaine with epinephrine 1:100,000 alkalinized at 9:1 ratio with a resulting pH of 7.21 using 8.4% sodium bicarbonate solution per manufacturer.
Onset
"The test solution will be made by a mixing pen called Onset- This mixing pen Onset will deliver 0.18 mL of sodium bicarbonate solution into the anesthetic cartridge."
Dental Clinic of Rainbow Center for Women and Children, Cleveland
Rainbow Babies and Children's Hospital, Cleveland
University Hospitals Cleveland Medical Center
OTHER