NCT05757557View on ClinicalTrials.gov

Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Disease

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

February 25, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

January 31, 2025

Conditions
Acute Kidney DiseaseChronic Kidney DiseaseCardiac SurgeryCardiopulmonary Bypass
Interventions
DRUG

Sham treatment

Sham treatment: Oxygen-air mixture without NO after intubation, during CPB, and for six hours after surgery.

DRUG

80-ppm NO

NO will be supplemented at 80-ppm concentration to cardiac surgery patients perioperatively after trachea intubation, during CPB, and for six hours after surgery.

Trial Locations (1)

634012

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk

All Listed Sponsors
lead

Tomsk National Research Medical Center of the Russian Academy of Sciences

OTHER

NCT05757557 - Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney Disease | Biotech Hunter | Biotech Hunter