Prevalence of Latent Tuberculosis Infection in Health-care Workers and Students

RecruitingOBSERVATIONAL
Enrollment

2,040

Participants

Timeline

Start Date

November 17, 2021

Primary Completion Date

June 30, 2026

Study Completion Date

December 15, 2026

Conditions
TuberculosisTuberculosis, PulmonaryTuberculosis InfectionLatent TuberculosisHealth Care Associated Infection
Interventions
DIAGNOSTIC_TEST

Prevalence of Latent Tuberculosis Infection

The prevalence of Latent Tuberculosis Infection \[LTBI\] is defined as 1) tuberculin conversion after a documented negative-baseline tuberculin skin test (TST), 2) positive result of the QuantiFERON-TB Gold (QFT) test performed \[higher response than the cut-off value of 0.35 IU / ml of INF-γ was detected in at least one test tube (TB1 or TB2)\], 3) chest imaging excluding pleural and/or pulmonary lesions suggestive of active tuberculosis and 4) final medical evaluation done by a Specialist in Infectious Diseases which excluded active disease. All four criteria must be met.

Trial Locations (1)

00168

RECRUITING

UOSD Allergologia e Immunologia Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma

All Listed Sponsors
lead

Eleonora Nucera

OTHER