Analgesia-First Sedation in Trauma Patients

NARecruitingINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

March 1, 2026

Study Completion Date

September 1, 2026

Conditions
Mechanical VentilationRespiratory Failure
Interventions
OTHER

Analgesia First Sedation Strategy for Mechanically Ventilated (MV) Trauma Subjects

"The Intervention is using a sedation strategy for MV trauma that initially targets pain by intermittent boluses followed by an IV drip only if required. Sedatives are limited to agitation management and for a limited duration as needed. This analgo-sedation approach differs from the approach of using IV drips of analgesics and sedatives simultaneously and discontinuing both once daily to assess subjects."

OTHER

Protocol Directed Sedation and Daily Sedation Interruption

The active comparator in this study is using a sedation strategy for MV trauma that uses IV drips of analgesics and sedatives simultaneously and discontinues both once daily to assess subjects.

Trial Locations (1)

90806

RECRUITING

Long Beach Memorial Medical Center, Long Beach

All Listed Sponsors
lead

MemorialCare Health System

OTHER