Optic Nerve Sheath Ultrasound in Giant Cell Arteritis

RecruitingOBSERVATIONAL
Enrollment

285

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

December 31, 2027

Study Completion Date

March 31, 2029

Conditions
Giant Cell ArteritisAnterior Ischemic Optic NeuropathyOptic Neuropathy, Ischemic
Interventions
DIAGNOSTIC_TEST

Optic nerve sheath ultrasound

The patients are examined in a supine relaxed position. The probe is gently placed on the closed eyelid with a standard ultrasound gel and adjusted to a suitable angle to display the optic nerve entry into the eyeball. Measurements are done 3mm distal to the posterior aspect of the ocular globe. Ultrasosonographic 14L5 probe is used with a safe thermal index, mechanical index and intensity limit. All patients will also undergo a bedside fundoscopic examination. Official ophthalmology consultation will be requested in patients with visual symptoms or abnormal fundoscopy.

DIAGNOSTIC_TEST

Standardized GCA assessment

Clinical assesment, blood test review, temporal/axillary artery ultrasound

Trial Locations (6)

N6A 4V2

NOT_YET_RECRUITING

St-Joseph's Health Care London, London

M5G 1X5

NOT_YET_RECRUITING

Sinai Health - Toronto, Toronto

H3G 1A4

NOT_YET_RECRUITING

MUHC - McGill University, Montreal

H4J1C5

RECRUITING

Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal

H4R 3K6

NOT_YET_RECRUITING

CIUSSS de l'Est-de-l'ile de Montreal, Montreal

H1T 2M4

NOT_YET_RECRUITING

CIUSSS de l'Estrie - CHUS, Sherbrooke

Sponsors
All Listed Sponsors
collaborator

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER

collaborator

Ciusss de L'Est de l'Île de Montréal

OTHER

collaborator

Estrie University Integrated Health and Social Services Center - University Hospital of Sherbrooke

OTHER

collaborator

Mount Sinai Hospital, Canada

OTHER

collaborator

St. Joseph's Health Care London

OTHER

collaborator

Ottawa Hospital Research Institute

OTHER

lead

Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

OTHER