Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 1, 2023

Primary Completion Date

April 1, 2026

Study Completion Date

April 1, 2026

Conditions
SchizophreniaHealthy
Interventions
DRUG

Intranasal insulin

160 IU insulin (Humalog) is administered intranasally using a metered spray bottle 15 minutes prior to the PET scan.

DRUG

Placebo

0.9% saline is administered intranasally using a metered spray bottle 15 minutes prior to the PET scan.

Trial Locations (1)

M6J1H3

RECRUITING

Centre for Addiction and Mental Health, Toronto

All Listed Sponsors
lead

Centre for Addiction and Mental Health

OTHER