A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

NARecruitingINTERVENTIONAL
Enrollment

205

Participants

Timeline

Start Date

September 29, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Obesity
Interventions
BEHAVIORAL

Weight loss

"A behavioral lifestyle program, up to 20 weeks in duration, based on interventions shown to be successful for weight loss such as the Diabetes Prevention Program (DPP), Action for Health in Diabetes (Look AHEAD), and Comprehensive Assessment of the Long-term Effects of Reducing Intake of Energy Study (CALERIE). Weekly sessions, led by experienced interventionists, will provide education and behavioral strategies for weight loss focused an energy-reduced diet and physical activity.~Participants must meet the following milestones to continue in the study:~* ≥ 2% weight loss anytime between 28 and 34 days after the start of the intervention~* ≥ 5% weight loss anytime between 140 and 146 days after the start of the intervention~* ≥ 7% weight loss by the end of 35 weeks~After achieving ≥7% weight loss followed by weight stability, participants are observed, without further intervention, for 52 weeks."

Trial Locations (3)

10032

RECRUITING

Columbia University Irving Medical Center, New York

19104

RECRUITING

Drexel University, Philadelphia

RECRUITING

University of Pennsylvania, Philadelphia

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

Tufts University

OTHER

collaborator

Columbia University

OTHER

collaborator

New York State Psychiatric Institute

OTHER

collaborator

Drexel University

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

Dartmouth College

OTHER

lead

University of Pittsburgh

OTHER