100
Participants
Start Date
May 15, 2021
Primary Completion Date
September 30, 2025
Study Completion Date
December 30, 2025
Skin biopsy
A punch skin biopsy of 3mm will be used to analyze cutaneous innervation
Cardiovascular Reflexes testing
Cardiovascular reflex tests including deep breathing, head-up Tilt, standing, isometric exercises, mental arithmetic and Valsalva maneuver.
Administration of clinical scales evaluating autonomic symptoms, pain small fiber neuropathy symptoms
We'll characterize patients' symptoms through the administration of clinical scales such as: SCOPA-AUT autonomic symptoms scale; Brief Pain Inventory questionnaire
Dinamic Sweat Test
Test for the functional assessment of postganglionic sudomotor pathway
RECRUITING
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Napoli
RECRUITING
ICS Maugeri - IRCCS of Telese Terme, Telese Terme
Istituti Clinici Scientifici Maugeri SpA
OTHER