Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

January 15, 2021

Primary Completion Date

January 15, 2025

Study Completion Date

January 16, 2025

Conditions
Macular HolesEpiretinal MembraneRetinal DetachmentMacular Dystrophies
Interventions
DIAGNOSTIC_TEST

Biometry

Biometric measurements performed with IOL Master, if executable Contact or immersion echobiometry if IOL Master cannot be performed

DIAGNOSTIC_TEST

Retinography (Color) + Autofluorescence (AF)

Colour + AF: EIDON, if available (60° not modulable) Colour: COBRA (60° non-modifiable) AF: Spectralis-Heidelberg (choose 55°) Other if available (choose posterior pole examination between 50-60°)

DIAGNOSTIC_TEST

OCT B-scan and OCT angiography (OCTA)

"OCT B-scan:~2 scans (6 mm)~1 cross line~OCTA:~3x3 mm + 6x6 mm centred on the fovea 4.5 mm centred on the optic nerve"

DIAGNOSTIC_TEST

Microperimetry

1\) fixation pattern 2) retinal sensitivity map

DIAGNOSTIC_TEST

Electrophysiological exams

Layer-by-layer assessment of the retina using focal ERG and pattern ERG according to standardised and published methods , For patients with visus \< 3/10 and unstable fixation a protocol based on component analysis of the photopic ERG from diffuse flash will be used.

Trial Locations (1)

00168

RECRUITING

Prof. Stanislao Rizzo, Rome

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER