The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans

NACompletedINTERVENTIONAL
Enrollment

194

Participants

Timeline

Start Date

March 29, 2023

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions
Memory Consolidation
Interventions
BEHAVIORAL

Congruent vs. Incongruent

The Congruent vs. Incongruent intervention relates to the feature-based structure of the novel categories (Modular or non-Modular) and whether there is (Congruent) or is not (Incongruent) a match between what was previously learned and the final target category.

BEHAVIORAL

Immediate vs. Awake vs. Asleep

Immediate, Awake, and Sleep refer to either no break, 2.5 hours awake, or 2 hours asleep plus a 30-minute post-nap break to account for sleep inertia between learning and target category.

BEHAVIORAL

Targeted memory reactivation (TMR)

Targeted memory reactivation (TMR) is the systematic presentation of sounds during sleep that were associated with certain stimuli during learning and will be administered either during slow wave sleep (SWS) or rapid eye movement (REM) sleep.

Trial Locations (1)

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Pennsylvania

OTHER