60
Participants
Start Date
April 15, 2023
Primary Completion Date
October 31, 2025
Study Completion Date
September 30, 2026
Transdermal Nicotine Patch
Participants will wear nicotine transdermal patches daily for 12-15 weeks. They will apply a study patch each morning and remove at bedtime. Active dose will titrate up from 3.5mg to 7mg, and then can optionally be further titrated to a maximum dose of 14mg. After week12, the dose will be slowly tapered over 2-3 weeks.
Transdermal Placebo Patch
Participants will wear placebo transdermal patches daily for 12-15 weeks. They will apply a study patch each morning and remove at bedtime. Placebo patch dose will titrate up from 3.5mg to 7mg, and then can optionally be further titrated to a maximum dose of 14mg. After week12, the dose will be slowly tapered over 2-3 weeks.
RECRUITING
Vanderbilt Psychiatric Hosptial, Nashville
National Institute of Mental Health (NIMH)
NIH
Vanderbilt University Medical Center
OTHER