Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster RCT

PHASE4RecruitingINTERVENTIONAL
Enrollment

3,000

Participants

Timeline

Start Date

September 17, 2024

Primary Completion Date

June 1, 2026

Study Completion Date

December 1, 2026

Conditions
Monkeypox
Interventions
DRUG

Bavarian Nordic smallpox vaccine

A single dose of the Bavarian Nordic smallpox vaccine will be given at baseline.

DRUG

Typhoid VI Polysaccharide Vaccine Injectable Solution

A single dose of the typhoid vaccine will be given at baseline.

Trial Locations (10)

Unknown

RECRUITING

Catholic University of Bukavu, Kinshasa

NOT_YET_RECRUITING

Federal Medical Center, Abuja

NOT_YET_RECRUITING

University of Abuja Teaching Hospital, Abuja

NOT_YET_RECRUITING

University of Ibadan, Ibadan

NOT_YET_RECRUITING

Irrua Specialist Teaching Hospital, Irrua

NOT_YET_RECRUITING

Aminu Kano Teaching Hospital, Kano

NOT_YET_RECRUITING

Lagos University Teaching Hospital, Lagos

NOT_YET_RECRUITING

Niger Delta Teaching Hospital, Okolobiri

NOT_YET_RECRUITING

University of Port Harcourt Teaching Hospital, Port Harcourt

NOT_YET_RECRUITING

Makerere University Lung Institute, Kampala

All Listed Sponsors
lead

McMaster University

OTHER