Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 15, 2022

Primary Completion Date

November 17, 2023

Study Completion Date

November 17, 2023

Conditions
AgingCognitive DeclineSarcopeniaFrailtyMuscle DegenerationPhysical Disability
Interventions
BEHAVIORAL

BFRT

Following a warm-up of 10 min, subjects in the experimental group will undergo BFRT for two times per week, consisting of lower extremity exercises (leg press, knee extension, knee flexion). BFRT will be at 40% of 1 repetition maximum (1RM); The volume % (V% = number of repetitions x number of sets x number of exercises x % 1 repetition max) = 57.6%. Progression during the 12 week program will be attained by a 1RM test every 4 weeks.

BEHAVIORAL

MDRT

Following a warm-up of 10 min, subjects in the experimental group will undergo MDRT for two times per week, consisting of lower extremity exercises (leg press, knee extension, knee flexion). The exercise will be at 80% of 1RM concentric-only or 120% of 1RM eccentric-only in a 3:1 ratio. The volume % (V% = number of repetitions x number of sets x number of exercises x % 1 repetition max) = 57.6%. Progression during the 12 week program will be attained by a 1RM test every 4 weeks.

Trial Locations (1)

LT 44221

Lithuanian Sports University, Kaunas

All Listed Sponsors
collaborator

Research Council of Lithuania

OTHER

collaborator

Lithuanian University of Health Sciences

OTHER

collaborator

Maastricht University

OTHER

collaborator

Vrije Universiteit Brussel

OTHER

collaborator

KU Leuven

OTHER

collaborator

Wingate Institute

OTHER

lead

Lithuanian Sports University

OTHER