Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans with Different Insulin Resistance Phenotypes

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 16, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Insulin ResistanceHypertriglyceridemia
Interventions
BEHAVIORAL

Standardized Dinner

De novo lipogenesis (DNL) will be assessed in all participants with a standardized dinner

BEHAVIORAL

Premeal exercise

DNL will be assessed in all participants with short bouts of premeal exercise with a standardized dinner

Trial Locations (1)

Unknown

RECRUITING

AMC Amsterdam, Amsterdam

All Listed Sponsors
collaborator

Amsterdam UMC

OTHER

collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Yale University

OTHER