Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France

RecruitingOBSERVATIONAL
Enrollment

500

Participants

Timeline

Start Date

August 8, 2024

Primary Completion Date

March 1, 2026

Study Completion Date

June 1, 2026

Conditions
Corneal Dystrophies
Interventions
GENETIC

Genotyping

Genotyping will measure the triple nucleotide repeat in the TCF4 gene and search for other known mutations in other genes Blood sample will be performed (genetic analyses).

DIAGNOSTIC_TEST

Histology

Histology will be performed on flat mounted Descemet membrane obtained after Descemetorhexis

OTHER

Collection of data

Collection of data of examination for diagnosis of the Fuchs Endothelial Corneal Dystrophy (FECD) including slit lamp results will be performed.

Trial Locations (1)

42055

RECRUITING

CHU Saint-Etienne, Saint-Etienne

All Listed Sponsors
collaborator

Kyoto University, Graduate School of Medicine

OTHER

lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER