Optimal Exercise Frequency to Reduce Liver Fat in Centrally Obese Adults With Non-Alcoholic Fatty Liver Disease

NARecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

March 2, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Non-Alcoholic Fatty Liver DiseaseObesity
Interventions
BEHAVIORAL

Once-a-week Exercise

Participants in this group will participate in a supervised treadmill exercise program delivered by certified fitness instructors. The prescribed program will involve one session weekly for 4 months, and the duration of vigorous-intensity treadmill exercise per session will be 75 min. Participants will exercise with an exercising heart rate at 6-7 metabolic equivalents (METs). Health information provided to the usual care control group will be made available to the participants in this group.

BEHAVIORAL

Thrice-a-week Exercise

Participants in this group will participate in a supervised treadmill exercise program delivered by certified fitness instructors. The prescribed program will involve three sessions weekly for 4 months, and the duration of vigorous-intensity treadmill exercise per session will be 25 min. Participants will exercise with an exercising heart rate at 6-7 METs. Health information provided to the usual care control group will be made available to the participants in this group.

OTHER

Usual Care Control

Participants in this group will receive health education delivered by research personnel. This program will consist of eight two-hour bi-weekly sessions covering major health issues relating to general health and NAFLD, such as non-communicable diseases, infectious diseases, and a healthy lifestyle.

Trial Locations (1)

Unknown

RECRUITING

LKS Faculty of Medicine, Hong Kong

All Listed Sponsors
lead

The University of Hong Kong

OTHER