Natural Orifice Specimen Extraction Surgery for Colorectal Cancer

NANot yet recruitingINTERVENTIONAL
Enrollment

318

Participants

Timeline

Start Date

March 1, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Colorectal Cancer
Interventions
PROCEDURE

Natural Orifice Specimen Extraction

After bowel resection, all bowel anastomoses are created via side-to-side intracorporeal anastomosis, either isoperistaltic or antiperistaltic. The surgical steps of NOSE with the transrectal method are illustrated in Figure 1. First, the rectosigmoid colonic lumen is blocked with a bowel clamp. After rectal irrigation with povidone-iodine water, a transanal endoscopic microsurgery (TEM) scope or Alexis wound protector is inserted through the anus, reaching the upper rectum. Enterotomy is performed at the upper rectum, and a suction device is used to clean any fecal spillage. The TEM scope is pushed forward beyond the rectal opening, and the specimen is extracted with the TEM scope. The rectal opening is closed with a barbed suture, and an air leak test is performed to identify anastomotic leakage.

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER

NCT05740267 - Natural Orifice Specimen Extraction Surgery for Colorectal Cancer | Biotech Hunter | Biotech Hunter