Restrictive Transfusion StratEgy Adjusted by SvO2 During Cardiac Surgery

NARecruitingINTERVENTIONAL
Enrollment

676

Participants

Timeline

Start Date

March 14, 2023

Primary Completion Date

November 19, 2025

Study Completion Date

December 12, 2025

Conditions
Cardiac SurgeryCardiopulmonary Bypass
Interventions
OTHER

Adjusted Transfusion

Patients assigned to the SvO2 group will be transfused if Hb concentration is lower than 9 g/dL and central SvO2 ≤ 65%. Transfusion will be repeated whenever Hb concentration is lower than 9 g/dL and central SvO2 ≤ 65% during surgery and in the ICU (until day 5). Central SvO2 will be measured on a blood sample obtained from the distal lumen of the central venous catheter. Oximetry will be used for measurement with a point-of-care of gas analysis.

Trial Locations (1)

34295

RECRUITING

Departement d'anesthésie et réanimation D - Arnaud de Villeneuve, Montpellier

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER