150
Participants
Start Date
January 1, 2023
Primary Completion Date
June 30, 2027
Study Completion Date
June 30, 2027
High-Intensity Treadmill Training
Participants will walk on a treadmill at a speed that produces 70-80% of age-adjusted heart rate reserve or a rating of perceived exertion of 17/20. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.
Treadmill Training with Perturbations
Participants will walk on a treadmill and a perturbation of the treadmill will be produced every 20s. Perturbations will randomly occur in the forward, backward, right or left directions, with a perturbation size set to 80% of stability threshold. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts with 2-3 minutes rest between bouts.
Standard Treadmill Training
Participants will walk on a treadmill at a speed that produces 30-40% of age-adjusted heart rate reserve. A total of 30, one hour sessions will be conducted. Training will be conducted in 10 minute bouts, with 2-3 minutes rest between bouts.
RECRUITING
Rehabilitation Hospital of Indiana, Indianapolis
RECRUITING
Marquette University, Milwaukee
Indiana University
OTHER
Medical College of Wisconsin
OTHER
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Marquette University
OTHER