NCT05731973 - Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

December 8, 2023

Primary Completion Date

January 31, 2025

Study Completion Date

September 30, 2025

Conditions

Pectus ExcavatumFunnel Chest

Interventions

PROCEDURE

Intercostal nerve cryoablation

Intercostal nerve cryoablation is applied during Nuss procedure.

DRUG

Thoracic epidural analgesia (continuous infusion with sufentanyl (1 µg/ml) and bupivacaine (1.25 mg/ml))

Thoracic epidural is placed prior to Nuss procedure

DRUG

Intercostal nerve block (single shot bupivacaine (1.25 mg/ml))

Single shot bupivacaine (1.25 mg/ml) intercostal nerve blocks are placed just anterior to the side of the cryoablation.

DRUG

Opioids (oxycodone with prolonged discharge 10 mg PO every 12 hours and oxycodone 5 mg every 6 hours, as needed)

Opioids

Trial Locations (1)

RECRUITING

Zuyderland Medical Center, Heerlen