274
Participants
Start Date
February 19, 2025
Primary Completion Date
February 29, 2028
Study Completion Date
April 30, 2028
Therapeutic Plasma Exchange (TPE)
"The TPE treatment will be initiated within 6 hrs after randomization. Duration of TPE treatment is approximately 120-180 minutes. An additional second TPE can be performed if the patient remains vasopressor dependent ≥ 0.4 ug/kg/min after 24 hours following the first TPE procedure.~Both unfractionated heparin (UFH) and citrate may be used as anticoagulant medication.~To ensure treatment comparability between different patients, we will replace plasma in a fixed ratio of 1.2 x the individual patient's total plasma fluid."
NOT_YET_RECRUITING
University Hospital Zurich, Zurich
RECRUITING
Hannover Medical School Anesthesiology, Hanover
RECRUITING
Hannover Medical School Internal Medicine, Hanover
RECRUITING
University Hospital Bonn, Bonn
NOT_YET_RECRUITING
University Hospital Heidelberg, Heidelberg
NOT_YET_RECRUITING
University Hospital Innsbruck, Innsbruck
NOT_YET_RECRUITING
University Hospital Vienna, Vienna
NOT_YET_RECRUITING
St. Joseph Hospital, Berlin
NOT_YET_RECRUITING
University Hospital Berlin Charite, Berlin
NOT_YET_RECRUITING
Hospital Braunschweig, Braunschweig
NOT_YET_RECRUITING
Hospital Bremerhaven, Bremerhaven
NOT_YET_RECRUITING
Hospital Cologne Meerheim, Cologne
NOT_YET_RECRUITING
University Hospital Cologne, Cologne
NOT_YET_RECRUITING
University Hospital Erlangen, Erlangen
NOT_YET_RECRUITING
University Hospital Essen, Essen
ACTIVE_NOT_RECRUITING
University Hospital Halle, Halle
NOT_YET_RECRUITING
University Hospital Hamburg (UKE), Hamburg
NOT_YET_RECRUITING
University Hospital Jena, Jena
NOT_YET_RECRUITING
University Hospital Kiel, Kiel
NOT_YET_RECRUITING
Hospital Magdeburg, Magdeburg
NOT_YET_RECRUITING
University Hospital Munich (TUM) Anesthesiology, Munich
NOT_YET_RECRUITING
University Hospital Munich (TUM) Internal Medicine, Munich
NOT_YET_RECRUITING
University Hospital Muenster Anesthesiology, Münster
NOT_YET_RECRUITING
University Hospital Rostock, Rostock
NOT_YET_RECRUITING
University Hospital Bern, Bern
Hannover Medical School
OTHER