Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical Trial

PHASE4Not yet recruitingINTERVENTIONAL

Enrollment

100

Participants

Timeline

Start Date

February 6, 2023

Primary Completion Date

February 6, 2025

Study Completion Date

February 6, 2026

Conditions

Helicobacter Pylori Infection

Interventions

DRUG

Vonoprazan

potassium-competitive acid blocker

DRUG

Amoxicillin, Metronidazole

Antibiotics for H. pylori eradication

DRUG

Bismuth Potassium Citrate

Gastric mucosal protective drug with anti-H. pylori effect

DRUG

Esomeprazole

Proton pump inhibitor

Trial Locations (1)

Shanghai East Hospital, Shanghai

All Listed Sponsors

lead

Shanghai East Hospital

OTHER