240
Participants
Start Date
May 26, 2023
Primary Completion Date
May 31, 2028
Study Completion Date
May 31, 2028
1. Standard spirometry
Spirometry is performed in two positions (sitting and supine) and three types of breathing (spontaneous, forced and slow).
2. 3D dynamic lung MRI at UTE in prone and supine positions
Dynamic lung MRI is performed for 3D MR spirometry while the subject is lying prone and supine before a reversibility test with salbutamol.
3. Reversibility test with salbutamol
Reversibility test with salbutamol administered using a pressurized metered dose bottle and an inhalation chamber at a dosage of 100 μg, 4 times (i.e., 400 μg in total).
4. 3D dynamic lung MRI at UTE in supine and prone position
Dynamic lung MRI is performed for 3D MR spirometry while the subject is lying prone and supine after the bronchodilatator's administration.
RECRUITING
"CEA , Service Hospitalier Fréderic Joliot"
Commissariat A L'energie Atomique
OTHER_GOV