Velusetrag for the Treatment of Chronic Intestinal Pseudo-Obstruction (CIPO).

PHASE2CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

December 15, 2021

Primary Completion Date

April 12, 2023

Study Completion Date

April 12, 2023

Conditions
Chronic Intestinal Pseudo-obstruction
Interventions
DRUG

Velusetrag 15 mg once daily for 4 weeks.

Subjects will be randomly allocated in a blinded fashion to 1 out of the 4 treatment sequences (each sequence include 4 periods, 2 periods with velusetrag and 2 periods with placebo). There will be a wash-out period between each treatment period.

DRUG

Placebo once daily for 4 weeks.

Subjects will be randomly allocated in a blinded fashion to 1 out of the 4 treatment sequences (each sequence include 4 periods, 2 periods with velusetrag and 2 periods with placebo). There will be a wash-out period between each treatment period.

Trial Locations (4)

30010

Aou Arcispedale Sant'Anna Di Cona, Cona

40128

Policlinico S.Orsola-Malpighi, Bologna

B3000

UZ Leuven Gasthuisberg Campus, Leuven

08035

Hospital General Vall Hebron, Barcelona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Alfasigma S.p.A.

INDUSTRY

NCT05724069 - Velusetrag for the Treatment of Chronic Intestinal Pseudo-Obstruction (CIPO). | Biotech Hunter | Biotech Hunter