Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

December 6, 2023

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
Colon CancerColorectal Cancer
Interventions
DRUG

MRTX849

Given by PO (mouth)

DRUG

Irinotecan

Given by IV (vein)

DRUG

Cetuximab

Given by IV (vein)

Trial Locations (1)

77030

M D Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mirati Therapeutics

UNKNOWN

lead

M.D. Anderson Cancer Center

OTHER