Does Testosterone Therapy Improve Patient-Reported Outcomes in Age-Related Testosterone Deficient Patients Undergoing Total Hip Replacement: A Randomized-Controlled Trial

PHASE3WithdrawnINTERVENTIONAL
0
Timeline

Start Date

November 1, 2019

Primary Completion Date

November 1, 2020

Study Completion Date

November 1, 2021

Conditions
Arthroplasty, Replacement, Hip
Interventions
DRUG

Testosterone Therapy

The testosterone pellet implantation will be performed 2 weeks before surgery. The dose is determined by baseline levels of sex hormone binding globulin (SHBG) in the following manner: If SHBG \> 60nmol/L implant 5 Testosterone Compounded 200mg (total 1000mgs testosterone). If SHBG 41-59 nmol/L implant 4 Testosterone Compounded 200mg (total 800mgs testosterone). If SHBG \<40 nmol/L implant 3 Testosterone Compounded 200mg (total 600mgs testosterone).

OTHER

No Testosterone Therapy

For the sham procedure no pellets will be implanted.

Trial Locations (1)

60018

American Hip Institute Research Foundation, Des Plaines

Sponsors
All Listed Sponsors
lead

American Hip Institute

OTHER