NCT05719831View on ClinicalTrials.gov

Optimization of Vonoprazan--amoxicillin Dual Therapy for Eradicating Helicobacter Pyloriinfection

PHASE3CompletedINTERVENTIONAL
Enrollment

516

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

September 30, 2023

Study Completion Date

September 30, 2023

Conditions
Helicobacter Pylori Eradication Rate
Interventions
DRUG

vonoprazan fumarate + high dose amoxicillin（H-10d）

vonoprazan fumarate 20 mg/time, 2 times/day, oral Amoxicillin 750mg/ time, 4 times/day, oral, for 10d

DRUG

vonoprazan fumarate + low dose amoxicillin（L-10d)

vonoprazan fumarate 20 mg/time, 2 times/day, oral Amoxicillin1000mg/ time, 2 times/day, oral, for 10d

DRUG

vonoprazan fumarate + amoxicillin（H-14d)

vonoprazan fumarate 20 mg/time, 2 times/day, oral Amoxicillin 750mg/ time, 4 times/day, oral, for 14d

Trial Locations (1)

510000

Sixth afflicated of Sun-yat sen university, Guangzhou

All Listed Sponsors
lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER