39
Participants
Start Date
January 15, 2024
Primary Completion Date
June 30, 2026
Study Completion Date
December 31, 2026
Précurseur de la dopamine
"In the first condition, volunteers will receive a 100mg dose of L-dopa, 25mg dose of Aromatic amino acid decarboxylase inhibitors (Benserazide) and 10mg dose of Domperidone. In the second condition, volunteers will receive Sulpiride 800mg. In the third condition, volunteers will receive placebo Reality-monitoring performances will be evaluated with a standardized task. Working-memory will be evaluated with the n-back task. Self-monitoring performances will be observed during a speech production experiment in which speakers monitor their auditory feedback while speaking.~Speech Bayesian reasoning: This task is a home-made task investigating the influence of prior on speech processing. Subjects will be required to identify speech in ambiguous auditory stimuli. Visual Bayesian reasoning: This task investigates the influence of prior on visual processing. Subjects will be required to recognize morph between faces and house."
antagoniste D2
In the second condition, volunteers will receive Sulpiride 800 mg
PLACEBO
In the third condition, volunteers will receive placebo
RECRUITING
Centre Hospitalier le Vinatier, Bron
Hôpital le Vinatier
OTHER