REALITY MONITORING

NARecruitingINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

January 15, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Neurosciences
Interventions
OTHER

Précurseur de la dopamine

"In the first condition, volunteers will receive a 100mg dose of L-dopa, 25mg dose of Aromatic amino acid decarboxylase inhibitors (Benserazide) and 10mg dose of Domperidone. In the second condition, volunteers will receive Sulpiride 800mg. In the third condition, volunteers will receive placebo Reality-monitoring performances will be evaluated with a standardized task. Working-memory will be evaluated with the n-back task. Self-monitoring performances will be observed during a speech production experiment in which speakers monitor their auditory feedback while speaking.~Speech Bayesian reasoning: This task is a home-made task investigating the influence of prior on speech processing. Subjects will be required to identify speech in ambiguous auditory stimuli. Visual Bayesian reasoning: This task investigates the influence of prior on visual processing. Subjects will be required to recognize morph between faces and house."

OTHER

antagoniste D2

In the second condition, volunteers will receive Sulpiride 800 mg

OTHER

PLACEBO

In the third condition, volunteers will receive placebo

Trial Locations (1)

69678

RECRUITING

Centre Hospitalier le Vinatier, Bron

All Listed Sponsors
lead

Hôpital le Vinatier

OTHER