NCT05710874View on ClinicalTrials.gov

A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.

NACompletedINTERVENTIONAL
Enrollment

107

Participants

Timeline

Start Date

September 23, 2016

Primary Completion Date

March 29, 2023

Study Completion Date

March 29, 2023

Conditions
White Spot LesionOrthodontic Appliance Complication
Interventions
OTHER

CPP-ACP paste

Daily application of CPP-ACP (Casein phosphopeptide amorphous calcium phosphate) paste (Tooth Mousse®) in addition to twice daily use of conventional toothpaste.

OTHER

CPP-ACPF paste

Daily application of CPP-ACPF (Casein phosphopeptide amorphous calcium phosphate in combination with fluoridepaste) (MI Paste Plus®) in addition to twice daily use of conventional toothpaste.

OTHER

1.25% fluoride gel

Weekly application of 1.25% fluoride gel (Elmex Medical Gel®) in addition to twice daily use of conventional toothpaste.

OTHER

Conventional

Twice daily use of conventional toothpaste.

Trial Locations (1)

9000

University of Ghent, Ghent

All Listed Sponsors
lead

University Hospital, Ghent

OTHER

NCT05710874 - A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding. | Biotech Hunter | Biotech Hunter