Transcutaneous Vagus Nerve Stimulation (tcVNS) in JIA

PHASE2CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

June 27, 2023

Primary Completion Date

November 13, 2024

Study Completion Date

January 15, 2025

Conditions
Juvenile Idiopathic Arthritis (JIA)
Interventions
DEVICE

Active tcVNS or Sham tcVNS

tcVNS is administered with a study device that gives off mild electrical impulses through the skin to stimulate the vagus nerve (a nerve that travels underneath the skin in your neck and head). This stimulation triggers a chemical response through the nerves and has been found to be effective in reducing pain and inflammation in several diseases.

DEVICE

Active tcVNS

tcVNS is administered with a study device that gives off mild electrical impulses through the skin to stimulate the vagus nerve (a nerve that travels underneath the skin in your neck and head). This stimulation triggers a chemical response through the nerves and has been found to be effective in reducing pain and inflammation in several diseases.

Trial Locations (7)

10016

Stephen D. Hassenfield Children's Center at NYU Langone Health, New York

11040

Cohen Children's Medical Center, Northwell Health, Lake Success

32827

Nemours Children's Health: Department of Pediatric Rheumatology, Orlando

46202

Indiana University, Indianapolis

84132

Division of Pediatric Rheumatology at the University of Utah School of Medicine and Primary Children's Hospital, Salt Lake City

94158

University of California San Francisco, San Francisco

98105

Seattle Children's Hospital, Seattle

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Autoimmunity Centers of Excellence (ACE)

UNKNOWN

collaborator

Northwell Health

OTHER

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH