NCT05707273View on ClinicalTrials.gov

CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

April 26, 2023

Primary Completion Date

July 24, 2026

Study Completion Date

July 24, 2026

Conditions
B Acute Lymphoblastic Leukemia
Interventions
DRUG

Autologous Anti-CD19 CAR-expressing T Lymphocytes

Given IV

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Bone Marrow Aspiration and Biopsy

Undergo bone marrow aspirate

DRUG

Cyclophosphamide

Given IV

DRUG

Fludarabine

Given IV

PROCEDURE

Leukapheresis

Undergo T-cell leukapheresis

OTHER

Questionnaire Administration

Complete questionnaires

Trial Locations (1)

91010

City of Hope Medical Center, Duarte

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER