NCT05704361View on ClinicalTrials.gov

A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis

PHASE1RecruitingINTERVENTIONAL
Enrollment

165

Participants

Timeline

Start Date

August 11, 2021

Primary Completion Date

April 28, 2027

Study Completion Date

April 28, 2027

Conditions
Multiple Sclerosis
Interventions
DRUG

RO7121932 IV

Participants will receive RO7121932, as an IV infusion, per the schedule specified in the treatment arms.

DRUG

RO7121932 SC

Participants will receive RO7121932, as SC injection, per the schedule specified in the treatment arms.

Trial Locations (32)

1200

RECRUITING

Cliniques Universitaires St-Luc, Brussels

9000

RECRUITING

UZ Gent, Ghent

11000

RECRUITING

University Clinical Center of Serbia, Belgrade

20132

RECRUITING

IRCCS Ospedale San Raffaele, Milan

20133

RECRUITING

Fond. Istituto Neurologico C.Besta, Milan

33612

WITHDRAWN

University of South Florida, Tampa

37075

COMPLETED

Universitätsmedizin Göttingen Georg-August-Universität, Göttingen

40006

RECRUITING

ARENSIA Exploratory Medicine, County Emergency Hospital, Cluj-Napoca

45267

WITHDRAWN

UC Health, LLC., Cincinnati

48149

RECRUITING

Universitätsklinikum Münster Klinik u. Poliklinik f. Neurologie, Münster

72076

RECRUITING

Universitätsklinikum Tübingen, Zentrum für Neurologie, Tübingen

81675

COMPLETED

Klinikum rechts der Isar der TU Muenchen, München

89081

RECRUITING

Universitätsklinikum Ulm, Ulm

94305

COMPLETED

Stanford University Medical Center, Stanford

6423906

WITHDRAWN

Tel Aviv Sourasky Medical Center, Tel Aviv

9112001

RECRUITING

Hadassah University Hospital - Ein Kerem, Jerusalem

06473

COMPLETED

Yale University Multiple Sclerosis Center, New Haven

01655

WITHDRAWN

University of Massachusetts Medical School, Worcester

H3A 2B4

RECRUITING

Montreal Neurological Institute and Hospital, Montreal

01307

ACTIVE_NOT_RECRUITING

"Universitätsklinikum Carl Gustav Carus", Dresden

MD-2025

RECRUITING

ARENSIA Exploratory Medicine Phase I, PMSI Republican Clinical Hospital, Chisinau

80-214

WITHDRAWN

Uniwersyteckie Centrum Kliniczne, Gda?sk

86-300

COMPLETED

Regionalny Szpital Specjalistyczny im. W. Bieganskiego, Grudzi?dz

60-693

ACTIVE_NOT_RECRUITING

MedPolonia, Poznan

70-111

RECRUITING

Osrodek Badan Klinicznych Euromedis, Szczecin

02-957

WITHDRAWN

Instytut Psychiatrii i Neurologii II Klinika Neurologiczna, Warsaw

41-800

RECRUITING

SPSK nr 1, Zabrze

4710-243

RECRUITING

Hospital de Braga, Braga

1169-050

RECRUITING

Hospital Santo Antonio dos Capuchos, Lisbon

4520-211

RECRUITING

Centro Hospitalar Entre o Douro e Vouga E.P.E. - Hospital de São Sebastião, Santa Maria da Feira

011658

RECRUITING

ARENSIA Exploratory Medicine SRL - Bucharest (Monza Medical Center), Bucharest

08035

RECRUITING

Hospital Universitari Vall dHebron (CEMCAT), Barcelona

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY