The UPDATE Trial (Uvb Phototherapy in Dermatology for ATopic Eczema)

NAActive, not recruitingINTERVENTIONAL
Enrollment

316

Participants

Timeline

Start Date

February 22, 2023

Primary Completion Date

January 30, 2026

Study Completion Date

December 31, 2026

Conditions
Atopic Dermatitis EczemaAtopic Dermatitis
Interventions
DEVICE

NB-UVB phototherapy

Narrowband ultraviolet B irradiation 3 times a week

COMBINATION_PRODUCT

Optimal topical therapy

A combination of detailed instructions about the disease and treatments by trained nurses, bathing and washing advices, adequate emollients use, avoidance of triggers (including possible and proven contact allergens), fingertip unit explanation for active topical therapy, and personalized topical therapy with different potency topical steroids, calcineurin inhibitors and tar ointments

Trial Locations (16)

1315RA

Flevoziekenhuis, Almere Stad

5223 GZ

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

1817 MS

Centrum Oosterwal, Alkmaar

1061 AE

OLVG, Amsterdam

1105 AZ

Amsterdam Universitair Medische Centra, Amsterdam

1105 BJ

Huid Medisch Centrum, Amsterdam

2015 BJ

Bergman Clinics, Haarlem

2134 TM

Spaarne Gasthuis, Hoofddorp

1441 RN

Dijklander Ziekenhuis, Purmerend

Unknown

Isala Klinieken, Zwolle

Alrijne Ziekenhuis, Leiderdorp

8934 AD

Medisch Centrum Leeuwarden, Leeuwarden

2625 AD

Reinier de Graaf Gasthuis, Delft

2333 ZA

Leids Universitair Medisch Centrum, Leiden

3015 GD

Erasmus Medisch Centrum, Rotterdam

3813 TZ

Meander Medisch Centrum, Amersfoort

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER