NCT05703685View on ClinicalTrials.gov

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

PHASE1RecruitingINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

June 22, 2023

Primary Completion Date

October 3, 2028

Study Completion Date

April 11, 2029

Conditions
Depression
Interventions
RADIATION

Lung scan

Immediately after the brain scan

DRUG

Apremilast

Oral administration of apremilast

DRUG

18F-PF-06445974

Injected IV followed by PET scanning

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Mental Health (NIMH)

NIH