The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma

PHASE4RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 18, 2023

Primary Completion Date

August 31, 2027

Study Completion Date

December 31, 2027

Conditions
PheochromocytomaParagangliomaAdrenalectomy; StatusAdrenergics Causing Adverse Effects in Therapeutic Use
Interventions
DRUG

Phenoxybenzamine

Patients in sham comparator group take a phenoxybenzamine at least 2 to 5 weeks before surgery. If blood pressure is more than 130/80 mmHg in the sitting position, the patient will take a more amount of phenoxybenzamine. If blood pressure is less than 90 mmHg in the standing position, the patient will take a less amount of phenoxybenzamine. In active comparator group, there is no drug to be taken.

Trial Locations (1)

Unknown

RECRUITING

Seoul National University Hospital, Seoul

All Listed Sponsors
lead

Seoul National University Hospital

OTHER