rhPro-UK in Acute Ischaemic Stroke Within 4.5 Hours of Stroke Onset Trial 2(PROST-2)

PHASE3CompletedINTERVENTIONAL
Enrollment

1,552

Participants

Timeline

Start Date

January 29, 2023

Primary Completion Date

March 14, 2024

Study Completion Date

March 14, 2024

Conditions
Acute Ischemic Stroke
Interventions
DRUG

rhPro-UK

35 mg, administered intravenously with a bolus of 15 mg within 3 minutes and the remainder by continuous infusion within 30 minutes

DRUG

rt-PA

0.9 mg/kg (maximum 90 mg), with 10% administered intravenously as a bolus, followed by 90% infusion within 1 hour

Trial Locations (72)

Unknown

Xuancheng People's Hospital, Xuancheng

Beijing Tiantan Hospital, Capital Medical University, Beijing

Xuanwu Hospital, Capital Medical University, Beijing

Huizhou First Hospital, Guangdong

Yuebei People's Hospital, Shaoguan

Handan Central Hospital, Handan

Hengshui People's Hospital (Harrison International Peace Hospital), Hengshui

Hebei General Hospital, Shijiazhuang

The First Hospital of Hebei Medical University, Shijiazhuang

The Second Hospital of Hebei Medical University, Shijiazhuang

Xingtai People's Hospital, Xingtai

The First Affiliated Hospital of Hebei North University, Zhangjiakou

Daqing Oilfield General Hospital, Daqing

Daqing People's Hospital, Daqing

Anyang People's Hospital, Anyang

Luoyang Central Hospital, Luoyang

First Affiliated Hospital of Nanyang Medical College, Nanyang

Nanshi Hospital of Nanyang, Nanyang

Nanyang Second General Hospital, Nanyang

General Hospital of Pingmei Shenma Medical Group, Pingdingshan

Xinxiang Central Hospital, Xinxiang

Zhumadian Central Hospital, Zhumadian

Tongji Hospital affiliated to Huazhong University of Science and Technology, Wuhan

Wuhan Fourth Hospital, Wuhan

Xiangyang Central Hospital, Xiangyang

Baogang Hospital of Inner Mongolia, Baotou

Baotou Central Hospital, Baotou

The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science & Technology, Baotou

Keshiketeng Hospital of Traditional Chinese Medicine and Mongolian Medicine, Chifeng

The Affiliated Hospital of Chifeng University, Chifeng

Affiliated Hospital of Inner Mongolia Medical University, Hohhot

The Affiliated Hospital of Nanjing University Medical School, Nanjing

General Hospital of Xuzhou Coal Mining Group, Xuzhou

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

Xuzhou Central Hospital, Xuzhou

Pingxiang People's Hospital, Pingxiang

Jilin Guowen Hospital, Changchun

The First Hospital of Jilin University, Changchun

The Second Hospital of Jilin University, Changchun

Meihekou Central Hospital, Meihekou

Jilin Neuropsychiatric Hospital, Siping

Tonghua Central Hospital, Tonghua

Ansteel Group General Hospital, Anshan

Benxi Central Hospital, Benxi

Beipiao Central Hospital, Chaoyang

Dalian Municipal Central Hospital, Dalian

Fukuang General Hospital of Liaoning Health Industry Group, Fushun

Fuxinkuang General Hospital of Liaoning Health Industry Group, Fuxin

The First Affiliated Hospital of Jinzhou Medical University, Jinzhou

Central Hospital Affiliated to Shenyang Medical College, Shenyang

The First People's Hospital of Shenyang, Shenyang

The People's Hospital of Liaoning Province, Shenyang

The PLA General Hospital of Northern Theater Command, Shenyang

Xianyang Hospital Of Yan'an University, Xianyang

Dezhou People's Hospital, Dezhou

Tengzhou Central People's Hospital, Dezhou

Shengli Oilfield Central Hospital, Dongying

Jinan City People's Hospital, Jinan

Liaocheng People's Hospital, Liaocheng

Linyi People's Hospital, Linyi

Tai'an Central Hospital, Tai’an

First People's Hospital of Tancheng, Tancheng

Yantai Yuhuangding Hospital, Yantai

Huashan Hospital, Fudan University, Shanghai

Sinopharm Tongmei General Hospital, Datong

Linfen Central Hospital, Linfen

Linfen People's Hospital, Linfen

West China Hospital of Sichuan University, Chengdu

Mianyang Central Hospital, Mianyang

Tianjin Huanhu Hospital, Tianjin

Taizhou First People's Hospital, Taizhou

Zhejiang Taizhou Hospital, Taizhou

All Listed Sponsors
lead

Tasly Biopharmaceuticals Co., Ltd.

INDUSTRY