A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection

NARecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

August 31, 2027

Study Completion Date

August 31, 2027

Conditions
Spontaneous Coronary Artery DissectionHealthy
Interventions
OTHER

Arterial Tonometry

We will measure arterial stiffness using arterial tonometry.

DIAGNOSTIC_TEST

Echocardiogram

We will collect limited ultrasound images of the heart.

DIAGNOSTIC_TEST

Carotid Ultrasounds

We will perform ultrasound imaging of the carotid artery.

DIAGNOSTIC_TEST

Elastography

We will measure the elastic properties of the arteries using elastography.

OTHER

Ankle-Brachial Index

We will measure the ankle-brachial index to assess peripheral artery blood flow.

OTHER

Microneurography with sympathoexcitatory maneuvers

We will measure sympathetic nerve activity at rest and in response to isometric handgrip, mental stress test, cold pressor test, Valsalva maneuvers.

Trial Locations (1)

55905

RECRUITING

Mayo Clinic Rochester, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Mayo Clinic

OTHER