A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression

Active, not recruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

May 4, 2023

Primary Completion Date

February 22, 2024

Study Completion Date

December 31, 2025

Conditions
Age Related Macular DegenerationIntermediate AMDAtrophyPrediction
Interventions
DIAGNOSTIC_TEST

Collection of both retrospective and prospective data collection in 3 visits.

3 clinic visits with multimodal imaging done at least at 6 months interval between 2 visits and meet the inclusion and exclusion criteria. Those with one visit remaining to complete 2 years, images will be acquired prospectively. In addition to the images, routine demographic data (age and sex) and available visual acuity (VA) (BCVA if possible, VA with Pinhole or VA with patient's glasses) will be collected. Multimodal imaging includes mandated macular OCT with or without enhanced depth imaging and infrared imaging. Fundus autofluorescence (AF) and multicolor imaging are optional. All imaging must be done on Heidelberg Spectralis system.

Trial Locations (25)

Unknown

Department of Ophthalmology, University Hospital, Nantes, Nantes

Department of Ophthalmology University of Bonn, Bonn

Department of Ophthalmology University of Freiburg, Freiburg im Breisgau

Department of Ophthalmology Justus/Liebig/University/Giessen, Giesen

Department of Ophthalmology St. Franziskus/Hospital Münster, Münster

Department of Ophthalmology University of Muenster Medical Center, Münster

Eye Clinic Sulzbach, Knappschaft Hospital Saar, Sulzbach

Royal Victoria Eye and Ear Research Foundation, Dublin

Medical Retina Service, Operative Unit Ophthalmology / MultiMedica Spa (IRCCSMM), Milan

Eye Unit, University Hospital Maggiore della Carità, Novara

Department of Ophthalmology University of Udine, Udine

Department of Ophthalmology Radboud University Medical Centre Nijmegen, Nijmegen

AIBILI-CEC (AIBILI- Clinical Trials Centre), Coimbra

Espaço Médico de Coimbra, Coimbra

Instituto de Oftalmologia Dr. Gama Pinto, Lisbon

Department of Ophthalmology Porto Medical School / Hospital S. João, Porto

Institut Català de Retina (ICR), Clinical Trial Unit, Barcelona

Institut de la Màcula Centro Médico Teknon, Barcelona

Valles Ophthalmology Research, S.L., Barcelona

Clínica Oftalmológica AIKEN / Fundación Aiken de la Comunitat Valenciana, Valencia

University Hospital Basel, University Eye Clinic, Basel, Basel

Swiss Visio Retina Research Center, Swiss Visio Montchoisi, Lausanne

Clinical Trial Unit, Dep. Ophth., Gloucestershire Hospitals NHS Foundation Trust, Cheltenham

Clinical Eye Research Centre - St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool

NIHR Moorfields Clinical Research Facility, Moorfields Eye Hospital, NHS Foundation Trust, London

All Listed Sponsors
collaborator

European Vision Institute Clinical Research Network

NETWORK

lead

Association for Innovation and Biomedical Research on Light and Image

OTHER