Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 6, 2023

Primary Completion Date

April 30, 2026

Study Completion Date

December 31, 2026

Conditions
Suicide
Interventions
DRUG

Ketamine Hydrochloride

100mg IM ketamine to be administered in conjunction with CRP. The ketamine injection will be administered first. Participants will be observed and have vital signs monitored for the first 45 minutes after administering medication in the ED, observing for immediate reactions. Afterwards, participants will continue to be monitored for potential late-term side effects on the inpatient unit. Ketamine will be given only after initial standard of care (SOC) treatment and screening studies have been initiated.

BEHAVIORAL

Crisis Response Plan

"Crisis Response Plan is a brief, empirically-validated, Cognitive-Behavioral Therapy-based one-time therapy, and its administration typically takes 30-60 minutes. It begins with a narrative assessment (allowing patients to tell their story) and concludes with collaboratively constructed plan that outlines strategies for the patient's self-management of future acute suicidal crises. Patients who engage in CRP are given an index card to keep with them that summarizes the emotional management strategies that they collaboratively generate with the CRP provider."

Trial Locations (1)

78229

RECRUITING

University Hospital, San Antonio

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

The University of Texas Health Science Center at San Antonio

OTHER