NCT05692661View on ClinicalTrials.gov

A Dose Escalation Study of Proton and Carbon Ion Irradiation for HER2 Positive and Triple Negative Breast Cancer

PHASE1RecruitingINTERVENTIONAL

Enrollment

24

Participants

Timeline

Start Date

January 10, 2023

Primary Completion Date

October 10, 2025

Study Completion Date

January 10, 2026

Conditions

Triple Negative Breast CancerHER2-positive Breast Cancer

Interventions

RADIATION

proton plus carbon ion radiotherapy

CTV1: whole breast, 40.05Gy(RBE) in 15 fractions with proton ion therapy; CTVboost: Tumor bed, carbon ion dose escalation study with four dose levels \[10.2Gy(RBE)/3Fx,10.8Gy(RBE) /3Fx,11.4Gy(RBE)/3Fx and 12Gy(RBE)/3Fx \].

Trial Locations (1)

Unknown

RECRUITING

Shanghai Proton and Heavy Ion center, Shanghai

All Listed Sponsors

lead

Shanghai Proton and Heavy Ion Center

OTHER